The proposed Yale School of Public Health?University of California Berkeley?Makerere University Pulmonary Complications of AIDS Research Training (PART) Program will support scientific and career development for medical doctors, scientists, laboratory technicians, and other research support personnel at the Makerere University College of Health Sciences (MAKCHS). The proposed training program, which builds on a >20-year history of collaboration in HIV/AIDS-related research and training between these institutions, will target junior investigators who are based at MAKCHS or affiliated non-governmental organizations and aspire to careers in patient-oriented research. The current renewal seeks to enhance opportunities in translational and implementation research, which have been identified by Ugandan and U.S. investigators as a critical under- represented need in Makerere's efforts to become an internationally recognized center of excellence for HIV- related lung disease research. By offering didactic training and practical research experiences with established HIV/AIDS investigators in externally funded projects, the program will prepare individuals from diverse professional backgrounds to contribute to translational and implementation research teams. This team-building strategy represents an efficient and forward-thinking approach to advancing research in the important, under- studied, and inherently inter-disciplinary content areas of TB and other pulmonary complications of HIV. Trainees will be enrolled in master's and doctoral degree programs and pre-doctoral research fellowships at MAKCHS, with their training supplemented by online coursework at external partner institutions, short international training visits for advanced courses and intensive laboratory experiences not available at MAKCHS. We will also offer advanced workshops and fellowships in implementation science in an executive- style educational format designed to accommodate busy junior faculty, post-doctoral fellows, and public health specialists working with implementing partners. All trainees will receive scientific and career mentoring through an individual research advisory committee and regular meetings with the program directors. The result of the training program will be an increase in the capacity of MAKCHS for conducting high-quality, locally relevant, and internationally recognized research on TB and other pulmonary complications of HIV. In turn, this will help improve HIV/AIDS outcomes in Uganda and other high-burden countries and develop the next generation of researchers.

Public Health Relevance

The proposed Yale School of Public Health?University of California Berkeley?Makerere University Pulmonary Complications of AIDS Research Training (PART) Program will train Ugandan investigators in clinical, translational, and implementation research on TB and other pulmonary complications of HIV. This will strengthen Makerere's capacity to conduct high quality, innovative, locally relevant HIV/AIDS research.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW009607-09
Application #
10098353
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Bansal, Geetha Parthasarathy
Project Start
2013-08-01
Project End
2023-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
9
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Yale University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Ggita, J M; Ojok, C; Meyer, A J et al. (2018) Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda. Int J Tuberc Lung Dis 22:530-536
Kizito, S; Katamba, A; Marquez, C et al. (2018) Quality of care in childhood tuberculosis diagnosis at primary care clinics in Kampala, Uganda. Int J Tuberc Lung Dis 22:1196-1202
Wayengera, Misaki; Kateete, David P; Asiimwe, Benon et al. (2018) Mycobacterium tuberculosis thymidylate kinase antigen assays for designating incipient, high-risk latent M.tb infection. BMC Infect Dis 18:133
Ayakaka, Irene; Ackerman, Sara; Ggita, Joseph M et al. (2017) Identifying barriers to and facilitators of tuberculosis contact investigation in Kampala, Uganda: a behavioral approach. Implement Sci 12:33
Cummings, M J; Goldberg, E; Mwaka, S et al. (2017) The sixth vital sign: HIV status assessment and severe illness triage in Uganda. Public Health Action 7:245-250
Kalema, Nelson; Lindan, Christina; Glidden, Dave et al. (2017) Predictors and short-term outcomes of recurrent pulmonary tuberculosis, Uganda: a cohort study. S Afr Respir J 23:106-112
Wayengera, Misaki; Mwebaza, Ivan; Welishe, Johnson et al. (2017) Immuno-diagnosis of Mycobacterium tuberculosis in sputum, and reduction of timelines for its positive cultures to within 3 h by pathogen-specific thymidylate kinase expression assays. BMC Res Notes 10:368
Armstrong-Hough, Mari; Turimumahoro, Patricia; Meyer, Amanda J et al. (2017) Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study. PLoS One 12:e0187145
Wayengera, Misaki; Mwebaza, Ivan; Welishe, Johnson et al. (2017) Sero-diagnosis of Active Mycobacterium tuberculosis Disease among HIV Co-infected Persons using Thymidylate Kinase based Antigen and Antibody Capture Enzyme Immuno-Assays. Mycobact Dis 7:
Cummings, Matthew J; Goldberg, Elijah; Mwaka, Savio et al. (2017) A complex intervention to improve implementation of World Health Organization guidelines for diagnosis of severe illness in low-income settings: a quasi-experimental study from Uganda. Implement Sci 12:126

Showing the most recent 10 out of 11 publications