Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
NIH Director’s New Innovator Awards (DP2)
Project #
1DP2OD001886-01
Application #
7429930
Study Section
Special Emphasis Panel (ZGM1-NDIA-G (02))
Program Officer
Basavappa, Ravi
Project Start
2007-09-30
Project End
2012-08-31
Budget Start
2007-09-30
Budget End
2012-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$2,355,000
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Srivastava, Shashikant; Gumbo, Tawanda (2018) Clofazimine for the Treatment of Mycobacterium kansasii. Antimicrob Agents Chemother 62:
Srivastava, Shashikant; Deshpande, Devyani; Gumbo, Tawanda (2017) Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. J Antimicrob Chemother 72:i20-i23
van Rijn, Sander P; Srivastava, Shashikant; Wessels, Mireille A et al. (2017) Sterilizing Effect of Ertapenem-Clavulanate in a Hollow-Fiber Model of Tuberculosis and Implications on Clinical Dosing. Antimicrob Agents Chemother 61:
Deshpande, Devyani; Srivastava, Shashikant; Musuka, Sandirai et al. (2016) Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases. Antimicrob Agents Chemother 60:4652-8
Srivastava, Shashikant; van Rijn, Sander P; Wessels, A Mireille A et al. (2016) Susceptibility Testing of Antibiotics That Degrade Faster than the Doubling Time of Slow-Growing Mycobacteria: Ertapenem Sterilizing Effect versus Mycobacterium tuberculosis. Antimicrob Agents Chemother 60:3193-5
Srivastava, Shashikant; Pasipanodya, Jotam G; Ramachandran, Geetha et al. (2016) A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies. EBioMedicine 6:126-138
Flamm, Robert K; Rhomberg, Paul R; Jones, Ronald N et al. (2015) In vitro activity of RX-P873 against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Antimicrob Agents Chemother 59:2280-5
Srivastava, Shashikant; Pasipanodya, Jotam; Sherman, Carleton M et al. (2015) Rapid drug tolerance and dramatic sterilizing effect of moxifloxacin monotherapy in a novel hollow-fiber model of intracellular Mycobacterium kansasii disease. Antimicrob Agents Chemother 59:2273-9
Gumbo, Tawanda; Pasipanodya, Jotam G; Wash, Peter et al. (2014) Redefining multidrug-resistant tuberculosis based on clinical response to combination therapy. Antimicrob Agents Chemother 58:6111-5
Pusch, Tobias; Pasipanodya, Jotam G; Hall 2nd, Ronald G et al. (2014) Therapy duration and long-term outcomes in extra-pulmonary tuberculosis. BMC Infect Dis 14:115

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