This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff.
SPECIFIC AIMS : 1. To consolidate and improve the efficiency of operation of two core research support facilities, the BSL-3 and the FACS Core Facility. 2. To facilitate and support the research of new faculty recruited to the institution who study areas of concern in women's health. 3. To continue to provide a safe and appropriate environment for the investigation of infectious agents such as HIV by supporting the BSL-3 facility on the Meharry Medical College campus. 4. To continue to provide technological infrastructure support to research utilizing methods in flow cytometry in the investigation of molecular biology of ovarian and breast cancer, as well as HIV infection and other areas of women's health research. Bindong Liu, Ph.D., will be the Core PI and he will commit 10% effort to the conduct of this activity. Dr. Liu is the current Director of the BSL-3/FACS Core Facility and is familiar with the operation and maintenance of it. He operates a BSL-2+ facility in his laboratory and has research experience with HIV-1. He will assist faculty, post docs and students develop their research methodology to achieve their objectives as well as training the technician on the use and application of new FACS procedures and protocol development in the BSL-3. Julia Shao, MD., Senior Research Assistant (RA). She is trained in data acquisition and analysis for day-to-day operation of the FACSCalibur. She assists investigators with projects involving flow cytometry. She is able to assist users in any cell sorting required as part of the HIV and AIDS-related infectious disease research or other projects requiring the cell sorting technology. As a highly skilled individual, she is also trained in BSL-3 procedures and is able to assist and train individuals who use that facility.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR003032-27
Application #
8357134
Study Section
Special Emphasis Panel (ZRR1-RI-B (01))
Project Start
2011-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
27
Fiscal Year
2011
Total Cost
$157,239
Indirect Cost
Name
Meharry Medical College
Department
Type
Schools of Medicine
DUNS #
041438185
City
Nashville
State
TN
Country
United States
Zip Code
37208
Popik, Waldemar; Khatua, Atanu; Hildreth, James E K et al. (2018) Phosphorodiamidate morpholino targeting the 5' untranslated region of the ZIKV RNA inhibits virus replication. Virology 519:77-85
Choudhury, Natasha A; DeBaun, Michael R; Ponisio, Maria R et al. (2018) Intracranial vasculopathy and infarct recurrence in children with sickle cell anaemia, silent cerebral infarcts and normal transcranial Doppler velocities. Br J Haematol 183:324-326
Ogunsile, Foluso J; Currie, Kelli L; Rodeghier, Mark et al. (2018) History of parvovirus B19 infection is associated with silent cerebral infarcts. Pediatr Blood Cancer 65:
Abney, Kristopher K; Ramos-Hunter, Susan J; Romaine, Ian M et al. (2018) Selective Activation of N,N'-Diacyl Rhodamine Pro-fluorophores Paired with Releasing Enzyme, Porcine Liver Esterase (PLE). Chemistry 24:8985-8988
Al-Hendy, Ayman; Laknaur, Archana; Diamond, Michael P et al. (2017) Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/?-Catenin Signaling Pathway. Endocrinology 158:592-603
Heerman, William J; Jackson, Natalie; Roumie, Christianne L et al. (2017) Recruitment methods for survey research: Findings from the Mid-South Clinical Data Research Network. Contemp Clin Trials 62:50-55
Kenerson, Donna; Fadeyi, Saudat; Liu, Jianguo et al. (2017) Processes in Increasing Participation of African American Women in Cancer Prevention Trials: Development and Pretesting of an Audio-Card. J Health Commun 22:933-941
Yang, Seung Woo; Cho, Eun Hee; Choi, So Young et al. (2017) DC-SIGN expression in Hofbauer cells may play an important role in immune tolerance in fetal chorionic villi during the development of preeclampsia. J Reprod Immunol 124:30-37
Erves, Jennifer Cunningham; Mayo-Gamble, Tilicia L; Hull, Pamela C et al. (2017) Erratum to: Adolescent Participation in HPV Vaccine Clinical Trials: Are Parents Willing? J Community Health 42:902
Mouton, Charles P; Southerland, Janet H (2017) Elder Abuse in the African Diaspora: A Review. J Natl Med Assoc 109:262-271

Showing the most recent 10 out of 225 publications