Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Objective I. Extend our current research team recruiting postdoctoral candidates, and enhancing their careers through a comprehensive developmental program AIM 1. Identify and recruit three suitable candidates.
AIM 2. Develop a research project and plan for each candidate from the current needs of the research group with consultation between the candidate and the PIs. Objective II. Establish the organizational structure necessary to enhance the research and the funding of the Nef Pathogenesis Group (NPG).
AIM 1. Establish an HIV/AIDS Pathogenesis Advisory Subcommittee.
AIM 2. Build research support for the group activities.
AIM 3. Organize the various components of HIV research at MSM AIM 4. Enhance our current proteomics and imaging capability to support research of the Pathogenesis group. Research Focus: Understanding the Role Played by and Mechanisms Underlying HIV-1 Nef's Pathogenic Effects Leading to AIDS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12RR003034-26
Application #
8357156
Study Section
Special Emphasis Panel (ZRR1-RI-B (02))
Project Start
2011-09-19
Project End
2012-06-30
Budget Start
2011-09-19
Budget End
2012-06-30
Support Year
26
Fiscal Year
2011
Total Cost
$237,335
Indirect Cost

  Institution

Name
Morehouse School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310

  Publications

Piano, Ilaria; Baba, Kenkichi; Claudia Gargini et al. (2018) Heteromeric MT1/MT2 melatonin receptors modulate the scotopic electroretinogram via PKC? in mice. Exp Eye Res 177:50-54
Owino, Sharon; Sánchez-Bretaño, Aida; Tchio, Cynthia et al. (2018) Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity. J Pineal Res 64:
Augello, Catherine J; Noll, Jessica M; Distel, Timothy J et al. (2018) Identification of novel blood biomarker panels to detect ischemic stroke in patients and their responsiveness to therapeutic intervention. Brain Res 1698:161-169
Greene, Sarah J (2018) The use and effectiveness of interactive progressive drawing in anatomy education. Anat Sci Educ 11:445-460
Chowdhury, Indrajit; Banerjee, Saswati; Driss, Adel et al. (2018) Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF-?B signaling pathway. J Cell Physiol :
Parker, Trisha C; Mohammed, Anaam; Leong, Traci et al. (2017) Rotavirus vaccination rate disparities seen among infants with acute gastroenteritis in Georgia. Ethn Health 22:585-595
Huang, Ming-Bo; Gonzalez, Ruben R; Lillard, James et al. (2017) Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells. Oncotarget 8:11302-11315
Sánchez-Bretaño, Aída; Baba, Kenkichi; Janjua, Uzair et al. (2017) Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3. Mol Vis 23:844-852
Hu, Guoku; Yelamanchili, Sowmya; Kashanchi, Fatah et al. (2017) Proceedings of the 2017 ISEV symposium on ""HIV, NeuroHIV, drug abuse, & EVs"". J Neurovirol 23:935-940
Laurent, Virgine; Sengupta, Anamika; Sánchez-Bretaño, Aída et al. (2017) Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium. Exp Eye Res 165:90-95

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