This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is felt that, based on the last five years achievements, made possible through the research partnership with the NIH-RCMI Program and recommendations of its advisory structures, the Universidad Central del Caribe (UCC) has been able to implement successfully its proposed strategic plan. This was directed toward strengthening and expanding its research capacity in the health sciences. This plan continues to operate under two interacting divisions. The Research Support Division comprises, the Office of the Assistant Dean for Research and Graduate Studies, which provides statistics, editing and consultant services;the Scientific Human Resources Development Unit, which aims at increasing the critical mass of researchers, establishing a mentoring and sabbatical program, and fostering clinical research;and the Common Instrumentation Area and Technical Services, which includes an expansion of the electronic workshop and the machine/carpentry shop, developing a continuous monitoring system of instruments and freezers and increasing research space at UCC. The Research Activity Division is constituted by research centers, for which funds are dedicated to improve substantially their specialized infrastructure to foster scientific studies relevant to the areas of Retrovirus, Substances of Abuse, Neurosciences and Cell and Molecular Biology. RCMI continuous support for the implementation of this plan has been essential;particularly, to accomplish previous and present research commitments of increasing significantly (in the last four years), peer-reviewed publications (20-53%), research funding (20%), and human (17 new research faculty) and physical resources (six new research laboratories).

Public Health Relevance

In the last two decades and a half, UCC Administration has strived to develop an environment capable of sustaining a competitive research endeavor by its faculty. This appeared to be an insurmountable task at the beginning. However, with the inception of the RCMI Program in 1986 and the insertion of human and physical resources, a more promising future was opened to this institution's research efforts. This is evidenced by the increased contribution to scientific knowledge by our researchers, mainly the areas of HIV/AIDS, substance of abuse, neuroscience and now in cancer. Without RCMI, UCC would have not been able to progress and contribute to these research fields.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12RR003035-24
Application #
7959223
Study Section
Special Emphasis Panel (ZRR1-RI-B (01))
Project Start
2009-09-15
Project End
2010-06-30
Budget Start
2009-09-15
Budget End
2010-06-30
Support Year
24
Fiscal Year
2009
Total Cost
$208,342
Indirect Cost
Name
Universidad Central Del Caribe
Department
Type
Other Domestic Higher Education
DUNS #
090534694
City
Bayamon
State
PR
Country
United States
Zip Code
00960
Karl, Anett; Agte, Silke; Zayas-Santiago, Astrid et al. (2018) Retinal adaptation to dim light vision in spectacled caimans (Caiman crocodilus fuscus): Analysis of retinal ultrastructure. Exp Eye Res 173:160-178
Agte, Silke; Savvinov, Alexey; Karl, Anett et al. (2018) Müller glial cells contribute to dim light vision in the spectacled caiman (Caiman crocodilus fuscus): Analysis of retinal light transmission. Exp Eye Res 173:91-108
Suárez-Arroyo, Ivette J; Loperena-Alvarez, Yaliz; Rosario-Acevedo, Raysa et al. (2017) Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer. Medicines (Basel) 4:
Maldonado-Martínez, Gerónimo; Hunter-Mellado, Robert F; Fernández-Santos, Diana et al. (2016) Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico. Int J Environ Res Public Health 13:ijerph13010050
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de la Parra, Columba; Castillo-Pichardo, Linette; Cruz-Collazo, Ailed et al. (2016) Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein. Nutr Cancer 68:154-64
Suárez-Arroyo, Ivette J; Rios-Fuller, Tiffany J; Feliz-Mosquea, Yismeilin R et al. (2016) Ganoderma lucidum Combined with the EGFR Tyrosine Kinase Inhibitor, Erlotinib Synergize to Reduce Inflammatory Breast Cancer Progression. J Cancer 7:500-11
Suárez-Arroyo, Ivette J; Feliz-Mosquea, Yismeilin R; Pérez-Laspiur, Juliana et al. (2016) The proteome signature of the inflammatory breast cancer plasma membrane identifies novel molecular markers of disease. Am J Cancer Res 6:1720-40
Pasaoglu, Taliha; Schikorski, Thomas (2016) Presynaptic size of associational/commissural CA3 synapses is controlled by fibroblast growth factor 22 in adult mice. Hippocampus 26:151-60

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