This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. CIAS has had a pivotal role in providing the infrastructure necessary to develop strong research programs that would otherwise be impossible at this small university. In particular, CIAS is a core area housing major equipment and the centralized cell culture facility. CIAS fosters equipment sharing, centralizes maintenance of equipment and provides repair for the equipment of all the projects. There are currently two technicians to see to the needs of the scientific community at UCC;An electronics technician and a machine shop operator handyman. The CIAS continues to be indispensable for the maintenance and future development of research at this institution. In this proposal, we requested funding to continue to conserve and upgrade the existing facilities and resources initially funded by RCMI including the common instrumentation, the electronics shop and the machine shop. In addition, we requested money to provide a temporary solution to the problem of limitations of space for research laboratories by renting trailers for laboratory space while we secure funding for a permanent addition to the UCC. Since receiving funding 5 years ago, we have provided laboratory space for two new investigators and have replaced obsolete equipment including a scintillation counter, a refrigerated table top centrifuge and a high speed refrigerated centrifuge. Moreover, we have developed and implemented a facilities monitoring system to continuously monitor the status of incubators, refrigerators and freezers. Three phases of this system are completely finished. These monitor the CIAS equipment, the repository freezers and other equipment housed in the basement, and the equipment of the Departments of Microbiology and Immunology and Pharmacology. The fourth phase of the system to monitor the Departments of Physiology and Anatomy is underway and expected to be completed in the next two months. The elements detailed above form the basis of our plan to maintain, fortify and expand our infrastructure for scientific research.

Public Health Relevance

The Common Instrumentation Area and Services (CIAS) is core area housing major equipment such as ultracentrifuges, freezers, spectrophotometers, and gamma counters, as well as the centralized cell culture facility. CIAS fosters equipment sharing, centralizes maintenance of equipment and provides repair for the equipment of all the projects and is supported by two technicians to see to the needs of the scientific community. The CIAS is indispensable for the maintenance and future development of research at UCC.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12RR003035-24
Application #
7959224
Study Section
Special Emphasis Panel (ZRR1-RI-B (01))
Project Start
2009-09-15
Project End
2010-06-30
Budget Start
2009-09-15
Budget End
2010-06-30
Support Year
24
Fiscal Year
2009
Total Cost
$113,458
Indirect Cost
Name
Universidad Central Del Caribe
Department
Type
Other Domestic Higher Education
DUNS #
090534694
City
Bayamon
State
PR
Country
United States
Zip Code
00960
Karl, Anett; Agte, Silke; Zayas-Santiago, Astrid et al. (2018) Retinal adaptation to dim light vision in spectacled caimans (Caiman crocodilus fuscus): Analysis of retinal ultrastructure. Exp Eye Res 173:160-178
Agte, Silke; Savvinov, Alexey; Karl, Anett et al. (2018) Müller glial cells contribute to dim light vision in the spectacled caiman (Caiman crocodilus fuscus): Analysis of retinal light transmission. Exp Eye Res 173:91-108
Suárez-Arroyo, Ivette J; Loperena-Alvarez, Yaliz; Rosario-Acevedo, Raysa et al. (2017) Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer. Medicines (Basel) 4:
Maldonado-Martínez, Gerónimo; Hunter-Mellado, Robert F; Fernández-Santos, Diana et al. (2016) Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico. Int J Environ Res Public Health 13:ijerph13010050
Zueva, Lidia; Golubeva, Tatiana; Korneeva, Elena et al. (2016) Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency. Microsc Microanal 22:379-86
Martinez, Namyr A; Ayala, Alondra M; Martinez, Magdiel et al. (2016) Caveolin-1 Regulates the P2Y2 Receptor Signaling in Human 1321N1 Astrocytoma Cells. J Biol Chem 291:12208-22
de la Parra, Columba; Castillo-Pichardo, Linette; Cruz-Collazo, Ailed et al. (2016) Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein. Nutr Cancer 68:154-64
Suárez-Arroyo, Ivette J; Rios-Fuller, Tiffany J; Feliz-Mosquea, Yismeilin R et al. (2016) Ganoderma lucidum Combined with the EGFR Tyrosine Kinase Inhibitor, Erlotinib Synergize to Reduce Inflammatory Breast Cancer Progression. J Cancer 7:500-11
Suárez-Arroyo, Ivette J; Feliz-Mosquea, Yismeilin R; Pérez-Laspiur, Juliana et al. (2016) The proteome signature of the inflammatory breast cancer plasma membrane identifies novel molecular markers of disease. Am J Cancer Res 6:1720-40
Pasaoglu, Taliha; Schikorski, Thomas (2016) Presynaptic size of associational/commissural CA3 synapses is controlled by fibroblast growth factor 22 in adult mice. Hippocampus 26:151-60

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