The Analytical Core laboratory at the Ponce School of Medicine will provide infrastructure to support basic and clinical research. The long term goal of this proposal is to provide efficient analytical services for the growing research needs of the institution and its affiliated clinical programs. The objectives of this proposal are to improve access to highly technical analytical tools, and to standardize and centralize the format to acquire specialized technical support for investigations in minority health care in Puerto Rico. The components of the Analytical Core Laboratory will consists of a Radioimmunoassay facility, and Gas Chromatography-Mass Spectrometry (GC-MS) laboratory. This proposal will aid in the development of the GC-MS and RIA laboratories as a fee-for- service facility. The organization of this facility will support research project development and will target potential clinical researchers. The availability of the proposed facility will encourage new project development in two ways: a) it will diminish the need of investigators to have, or develop, specific analytical skills, and b) it will make personnel available for consultation and project design. Furthermore, this program will improve support of new research initiatives through the centralization of analytical services. The development of new projects will in turn support the facility by providing new source of revenue under fees-for-service.

Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Cuevas, Marielly; Cruz, Myrella L; Ramirez, Antonio E et al. (2018) Stress During Development of Experimental Endometriosis Influences Nerve Growth and Disease Progression. Reprod Sci 25:347-357
Jimenez-Torres, Gladys J; Wojna, Valerie; Rosario, Ernesto et al. (2017) Assessing health-related resiliency in HIV+ Latin women: Preliminary psychometric findings. PLoS One 12:e0181253
Isidro, Raymond A; Lopez, Abdon; Cruz, Myrella L et al. (2017) The Probiotic VSL#3 Modulates Colonic Macrophages, Inflammation, and Microflora in Acute Trinitrobenzene Sulfonic Acid Colitis. J Histochem Cytochem 65:445-461
de Jesus, Edelmarie Rivera; Isidro, Raymond A; Cruz, Myrella L et al. (2016) Adoptive Transfer of Dendritic Cells Expressing Fas Ligand Modulates Intestinal Inflammation in a Model of Inflammatory Bowel Disease. J Clin Cell Immunol 7:
Abreu-Delgado, Yamilka; Isidro, Raymond A; Torres, Esther A et al. (2016) Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease. World J Gastroenterol 22:3581-91
Couvertier-Lebron, Carmen E; Dove, Rachel; Acevedo, Summer F (2016) What You Do Not Know Could Hurt You: What Women Wish Their Doctors Had Told Them About Chemotherapy Side Effects on Memory and Response to Alcohol. Breast Cancer (Auckl) 10:229-238
Isidro, Raymond A; Cruz, Myrella L; Isidro, Angel A et al. (2015) Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia. World J Gastroenterol 21:1749-58
Norman, Lisa R; Basso, Michael (2015) An Update of the Review of Neuropsychological Consequences of HIV and Substance Abuse: A Literature Review and Implications for Treatment and Future Research. Curr Drug Abuse Rev 8:50-71
Colón-Caraballo, Mariano; Monteiro, Janice B; Flores, Idhaliz (2015) H3K27me3 is an Epigenetic Mark of Relevance in Endometriosis. Reprod Sci 22:1134-42
Quiñones, Maria; Urrutia, Rebecca; Torres-Reverón, Annelyn et al. (2015) Anxiety, coping skills and hypothalamus-pituitary-adrenal (HPA) axis in patients with endometriosis. J Reprod Biol Health 3:

Showing the most recent 10 out of 171 publications