The overall goal of the Core Services for Biomedical Research (CSBR) is to provide multidisciplinary research resources to TU scientists. These are an Electron Microscopy, Image Analysis, Cell Sorting service facilities, and a Cell Culture and Molecular Biology Laboratory complex. By continuing to provide these services, which are already in place, to TU researchers, the CSBR intends to provide needed technical support to researchers, strengthen the university's capability in competitive research, and promote interdisciplinary biomedical research. Specifically the aim is to provide a well maintain ' ed, competently staffed, core service facility for electron microscopy research, by maintaining a transmission (Philips 201) and scanning electron microscope (Phillips 505) in excellent working condition and under manufacturer service contract; and providing skilled electron microscopy technical assistance in areas of sample preparation, sectioning, microscope use, and photomicrography and printing. In the area of Image analysis the ain is to provide access to advanced image analysis and data collection technology by maintaining a computer-based image analysis system in working, providing skilled technical assistance in data collection, assistance in data manipulation and presentation. and the instrumentation and software for PC-based image acquisition and analysis. This unit will also provide services as the central resource for the planning, purchasing, and installation and support of computer hardware, software, and network equipment for RCMI scientists. and maintain a Coulter Elite flow cytometer and work station, provide competent staffing for the various applications performed, and to provide scientific collaboration *in areas of experimental design, sample preparation, fluorochrome selection, instrument configuration, and data analysis.

Project Start
2001-06-01
Project End
2002-05-31
Budget Start
Budget End
Support Year
14
Fiscal Year
2002
Total Cost
$116,317
Indirect Cost
Name
Tuskegee University
Department
Type
DUNS #
128214178
City
Tuskegee
State
AL
Country
United States
Zip Code
36088
Mukherjee, Angana; Hollern, Daniel P; Williams, Oluwasina G et al. (2018) A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis. Front Cell Dev Biol 6:69
Yates, Clayton; Long, Mark D; Campbell, Moray J et al. (2017) miRNAs as drivers of TMPRSS2-ERG negative prostate tumors in African American men. Front Biosci (Landmark Ed) 22:212-229
Chowdhury, Rupak; David, Nganwa; Bogale, Asseged et al. (2016) Assessing the Key Attributes of Low Utilization of Mammography Screening and Breast-self Exam among African-American Women. J Cancer 7:532-7
Jones, Jacqueline; Mukherjee, Angana; Karanam, Balasubramanyam et al. (2016) African Americans with pancreatic ductal adenocarcinoma exhibit gender differences in Kaiso expression. Cancer Lett 380:513-22
Wang, Honghe; Liu, Wei; Black, ShaNekkia et al. (2016) Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression. Oncotarget 7:5677-89
Reams, R Renee; Jones-Triche, Jacqueline; Chan, Owen T M et al. (2015) Immunohistological analysis of ABCD3 expression in Caucasian and African American prostate tumors. Biomed Res Int 2015:132981
Arora, Ritu; Schmitt, David; Karanam, Balasubramanyam et al. (2015) Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers. Oncotarget 6:662-78
Jones, Jacqueline; Wang, Honghe; Karanam, Balasubramanyam et al. (2014) Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas. Clin Exp Metastasis 31:497-510
Okumu, Lilian A; Braden, Tim D; Vail, Krystal et al. (2014) Low androgen induced penile maldevelopment involves altered gene expression of biomarkers of smooth muscle differentiation and a key enzyme regulating cavernous smooth muscle cell tone. J Urol 192:267-73
Theodore, Shaniece C; Davis, Melissa; Zhao, Fu et al. (2014) MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1. Oncotarget 5:3512-25

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