This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In critiquing the research agenda associated with increasing physical activity levels among Americans, Baranowski et al. (1998) state that it is crucial to demonstrate that a particular theory / construct accounts for significant variance (i.e., 30%) in a target behavior (e.g., moderate-intensity physical activity) before theoretically-based interventions can be successfully developed. Furthermore, Baranowski et al. (1998) and Healthy People 2010 suggest that the moderating impact of ethnicity on the theory / target behavior relationship is an important issue to consider, particularly in post-secondary institutions. African-Americans are more sedentary compared to Caucasians, which places them at greater risk for developing various chronic diseases. The purpose of the proposed studies is to use the theory of planned behavior (TPB) to identify key global determinants (i.e., attitudes, subjective norms, perceived behavioral control) and accessible beliefs (i.e., behavioral, normative, control) in college-aged African-Americans and Caucasians. These findings will allow future researchers to focus on developing ethnically relevant physical activity interventions. Four studies will be conducted to achieve this goal. First, a pilot study will be conducted to generate the accessible beliefs proposed by the TPB. These beliefs will be put into questionnaire format and tested in a second study for comprehension and readability. Next, the test-retest reliability of the modified questionnaire from study two will be examined in study three. Finally, the fourth study will administer the TPB questionnaire to 416 African-Americans and 416 Caucasians who will be followed up at three and six months. This research plan will allow us to assess which determinants and beliefs are associated with moderate-intensity physical activity levels in both groups.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR003062-20
Application #
7336082
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-06-01
Project End
2007-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
20
Fiscal Year
2006
Total Cost
$94,130
Indirect Cost
Name
Clark Atlanta University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
065325177
City
Atlanta
State
GA
Country
United States
Zip Code
30314
Morton, Derrick J; Patel, Divya; Joshi, Jugal et al. (2017) ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation. Oncotarget 8:2536-2549
Joshi, Jugal Bharat; Patel, Divya; Morton, Derrick J et al. (2017) Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52. Mol Oncol 11:337-357
Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H; Morton, Derrick J et al. (2016) ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells. Biochem Biophys Res Commun 478:60-66
Wilder, Catera L; Walton, Charlene; Watson, Valencia et al. (2016) Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells. Int J Biochem Cell Biol 79:199-208
Brown, Shanora G; Knowell, Ashley E; Hunt, Aisha et al. (2015) Interferon inducible antiviral MxA is inversely associated with prostate cancer and regulates cell cycle, invasion and Docetaxel induced apoptosis. Prostate 75:266-79
Muniyan, Sakthivel; Chou, Yu-Wei; Tsai, Te-Jung et al. (2015) p66Shc longevity protein regulates the proliferation of human ovarian cancer cells. Mol Carcinog 54:618-31
Chinaranagari, Swathi; Sharma, Pankaj; Bowen, Nathan J et al. (2015) Prostate cancer epigenome. Methods Mol Biol 1238:125-40
Burton, Liza J; Smith, Basil A; Smith, Bethany N et al. (2015) Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells. Carcinogenesis 36:1019-27
Goodson 3rd, William H; Lowe, Leroy; Carpenter, David O et al. (2015) Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis 36 Suppl 1:S254-96
Mandal, S; Abebe, F; Chaudhary, J (2014) -174G/C polymorphism in the interleukin-6 promoter is differently associated with prostate cancer incidence depending on race. Genet Mol Res 13:139-51

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