In recent years, the Analytical Core Laboratory (ACL) has significantly contributed to the success of the RCMI Program. During the current grant period, the ACL has provided analytical services to 2 pilot project Pis (Drs. Hamme and Liu) and 17 other faculty members as well as a large number of research associates, technicians, and students in the College of Science, Engineering, and Technology (CSET). These ACL users have been very active in publishing peer- reviewed papers (over 110 in last 5 years) and presenting over 200 papers in national or international conferences during the same period. In addition, faculty members using the ACL are currently receiving twenty two (22) research grants. In order to further improve the productivity of these faculty and to meet the biomedical and environmental health research needs of ACL users, the following plans are proposed: (1) ACL will provide laboratory support for 3 new RCMI pilot projects and contribute to career development for their Pis (Drs. Arslan, Gao &Hossain) and collaborators;(2) ACL will implement a more comprehensive approach to provide better services to its user community;(3) ACL will offer workshops for major equipment including LC/MS/MS, CE/MS/MS, LC-ICP/MS, Raman microscopy system, and FT-IR as well as other conventional instruments at least once a semester;(4) ACL plans to acquire three new equipments as well as computers and printers to satisfy the needs of its user community;(5) ACL plans to renovate two lab spaces for accommodating new equipments, making its operation more efficient, and providing a safer environment for its users;(6) ACL will expand the role of the Analytical Users Committee for improving the quality of its service by maximizing resources and establishing a solid system for cost recovery;and (7) ACL will use a more efficient cost recovery system in order to move towards fiscal independence. The improved services as outlined in this proposal and the requested new equipment will help three pilot projects (Drs. Arslan, Gao, Hossain) as well as other ACL faculty users including Drs. Campbell, Hamme, Lee, Liu, Ray, Tachikawa, Yu, Venkatraman, Patlolla, Hwang, M. Begonia, G. Begonia, Li, and several other faculty members in CSET to further improve the productivity of their research in environmental health.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Research Centers in Minority Institutions Award (G12)
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Special Emphasis Panel (ZRR1-RI-1 (01))
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Jackson State University
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United States
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Denmark, Iris S; Begu, Ermira; Arslan, Zikri et al. (2018) Removal of inorganic mercury by selective extraction and coprecipitation for determination of methylmercury in mercury-contaminated soils by chemical vapor generation inductively coupled plasma mass spectrometry (CVG-ICP-MS). Anal Chim Acta 1041:68-77
Arslan, Zikri; Oymak, Tulay; White, Jeremy (2018) Triethylamine-assisted Mg(OH)2 coprecipitation/preconcentration for determination of trace metals and rare earth elements in seawater by inductively coupled plasma mass spectrometry (ICP-MS). Anal Chim Acta 1008:18-28
White, Jeremy; Çelik, Ahmet; Washington, Robert et al. (2018) Sequential coprecipitation and matrix removal for determination of cadmium impurities from multivitamin supplements by inductively coupled plasma mass spectrometry and method validation by isotope dilution analysis of SRM 3280 multivitamin/multielement ta Microchem J 139:242-249
Rhaman, Md Mhahabubur; Hasan, Mohammad H; Alamgir, Azmain et al. (2018) Highly selective and sensitive macrocycle-based dinuclear foldamer for fluorometric and colorimetric sensing of citrate in water. Sci Rep 8:286
Johnson, Martha; Ates, Mehmet; Arslan, Zikri et al. (2017) Assessment of Crystal Morphology on Uptake, Particle Dissolution, and Toxicity of Nanoscale Titanium Dioxide on Artemia salina. J Nanotoxicol Nanomed 2:11-27
Portis, Bobby; Mirchi, Ali; Emami Khansari, Maryam et al. (2017) An Ideal C3-Symmetric Sulfate Complex: Molecular Recognition of Oxoanions by m-Nitrophenyl- and Pentafluorophenyl-Functionalized Hexaurea Receptors. ACS Omega 2:5840-5849
Antwi-Boasiako, Afua A; Dunn, Derrick; Dasary, Samuel S R et al. (2017) Bioconjugated graphene oxide-based Raman probe for selective identification of SKBR3 breast cancer cells. J Raman Spectrosc 48:1056-1064
Sweet, Carrie; Pramanik, Avijit; Jones, Stacy et al. (2017) Two-Photon Fluorescent Molybdenum Disulfide Dots for Targeted Prostate Cancer Imaging in the Biological II Window. ACS Omega 2:1826-1835
Kaya, Hasan; Duysak, Müge; Akbulut, Mehmet et al. (2017) Effects of subchronic exposure to zinc nanoparticles on tissue accumulation, serum biochemistry, and histopathological changes in tilapia (Oreochromis niloticus). Environ Toxicol 32:1213-1225
Yilmaz, Vedat; Yilmaz, Hayriye; Arslan, Zikri et al. (2017) Novel Imprinted Polymer for the Preconcentration of Cadmium with Determination by Inductively Coupled Plasma Mass Spectrometry. Anal Lett 50:482-499

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