Abstract

The long term objective of this project is to provide faculty at the University of Texas at San Antonio with the needed capabilities for using the UTSA Transmission Electron Microscope Facility in their individual research projects.
The specific aims of this proposal are 1) to maximize the capacity of the UTSA Transmission Electron Microscope (TEM) Facility for tissue sectioning; and, 2) to provide assistance to faculty for routine embedding, sectioning and photography in order to increase research productivity at the institution. Electron microscopy provides an invaluable technique for localizing both structures and molecules at the subcellular level. There are currently a number of faculty in the Division of Life Sciences at the University of Texas at San Antonio who use, or plan to use, electron microscopy in their research. To accomplish the specific aims of the present proposal, the capacity of the UTSA TEM Facility will be increased by purchasing a rotary microtome. In addition, assistance will be provided for the following routine tasks: tissue fixation, tissue embedding, thick sectioning, thin sectioning, sample analysis, photography and printing. With the increased capacity and available technical assistance, faculty will be able to complete ultrastructural studies in a timely fashion. thereby increasing their research capabilities, and, ultimately, their research productivity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
3G12RR013646-02S1
Application #
6310170
Study Section
Project Start
1999-09-30
Project End
2000-09-29
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
2
Fiscal Year
2000
Total Cost
$109,103
Indirect Cost

  Institution

Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78249

  Publications

Ye, Ruquan; Dong, Juncai; Wang, Luqing et al. (2018) Manganese deception on graphene and implications in catalysis. Carbon N Y 132:623-631
Everett, James; Collingwood, Joanna F; Tjendana-Tjhin, Vindy et al. (2018) Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale 10:11782-11796
Ortega, Eduardo; Ponce, Arturo; Santiago, Ulises et al. (2017) Structural damage reduction in protected gold clusters by electron diffraction methods. Adv Struct Chem Imaging 2:12
Rodriguez, Roberto A; Chen, Liao Y; Plascencia-Villa, Germán et al. (2017) Elongation affinity, activation barrier, and stability of A?42 oligomers/fibrils in physiological saline. Biochem Biophys Res Commun 487:444-449
Mimun, L Christopher; Ajithkumar, G; Rightsell, Chris et al. (2017) Synthesis and characterization of Na(Gd0.5Lu0.5)F4: Nd3+,a core-shell free multifunctional contrast agent. J Alloys Compd 695:280-285
Raphael, Itay; Webb, Johanna; Gomez-Rivera, Francisco et al. (2017) Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis. Front Immunol 8:812
Srinivasan, Anand; Torres, Nelson S; Leung, Kai P et al. (2017) nBioChip, a Lab-on-a-Chip Platform of Mono- and Polymicrobial Biofilms for High-Throughput Downstream Applications. mSphere 2:
Rozinek, Sarah C; Thomas, Robert J; Brancaleon, Lorenzo (2016) Biophysical characterization of the interaction of human albumin with an anionic porphyrin. Biochem Biophys Rep 7:295-302
Plascencia-Villa, Germán; Ponce, Arturo; Collingwood, Joanna F et al. (2016) High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep 6:24873
Mendoza-Cruz, Rubén; Bazán-Díaz, Lourdes; Velázquez-Salazar, J Jesús et al. (2016) Helical Growth of Ultrathin Gold-Copper Nanowires. Nano Lett 16:1568-73

Showing the most recent 10 out of 181 publications