Abstract

The long term objective of this project is to provide faculty at the University of Texas at San Antonio with the needed capabilities for using the UTSA Transmission Electron Microscope Facility in their individual research projects.
The specific aims of this proposal are 1) to maximize the capacity of the UTSA Transmission Electron Microscope (TEM) Facility for tissue sectioning; and, 2) to provide assistance to faculty for routine embedding, sectioning and photography in order to increase research productivity at the institution. Electron microscopy provides an invaluable technique for localizing both structures and molecules at the subcellular level. There are currently a number of faculty in the Division of Life Sciences at the University of Texas at San Antonio who use, or plan to use, electron microscopy in their research. To accomplish the specific aims of the present proposal, the capacity of the UTSA TEM Facility will be increased by purchasing a rotary microtome. In addition, assistance will be provided for the following routine tasks: tissue fixation, tissue embedding, thick sectioning, thin sectioning, sample analysis, photography and printing. With the increased capacity and available technical assistance, faculty will be able to complete ultrastructural studies in a timely fashion. thereby increasing their research capabilities, and, ultimately, their research productivity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR013646-05
Application #
6652867
Study Section
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
5
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78249

  Publications

Ye, Ruquan; Dong, Juncai; Wang, Luqing et al. (2018) Manganese deception on graphene and implications in catalysis. Carbon N Y 132:623-631
Everett, James; Collingwood, Joanna F; Tjendana-Tjhin, Vindy et al. (2018) Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale 10:11782-11796
Ortega, Eduardo; Ponce, Arturo; Santiago, Ulises et al. (2017) Structural damage reduction in protected gold clusters by electron diffraction methods. Adv Struct Chem Imaging 2:12
Rodriguez, Roberto A; Chen, Liao Y; Plascencia-Villa, Germán et al. (2017) Elongation affinity, activation barrier, and stability of A?42 oligomers/fibrils in physiological saline. Biochem Biophys Res Commun 487:444-449
Mimun, L Christopher; Ajithkumar, G; Rightsell, Chris et al. (2017) Synthesis and characterization of Na(Gd0.5Lu0.5)F4: Nd3+,a core-shell free multifunctional contrast agent. J Alloys Compd 695:280-285
Raphael, Itay; Webb, Johanna; Gomez-Rivera, Francisco et al. (2017) Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis. Front Immunol 8:812
Srinivasan, Anand; Torres, Nelson S; Leung, Kai P et al. (2017) nBioChip, a Lab-on-a-Chip Platform of Mono- and Polymicrobial Biofilms for High-Throughput Downstream Applications. mSphere 2:
Moritz, Robert J; LeBaron, Richard G; Phelix, Clyde F et al. (2016) Macrophage TGF-?1 and the Proapoptotic Extracellular Matrix Protein BIGH3 Induce Renal Cell Apoptosis in Prediabetic and Diabetic Conditions. Int J Clin Med 7:496-510
Vall-Sagarra, Alicia; McMicken, Brady; Nonell, Santi et al. (2016) Effects of Visible-Light Irradiation of Protoporphyrin?IX on the Self-Assembly of Tubulin Heterodimers. Chemphyschem 17:3269-3282
Rozinek, Sarah C; Thomas, Robert J; Brancaleon, Lorenzo (2016) Biophysical characterization of the interaction of human albumin with an anionic porphyrin. Biochem Biophys Rep 7:295-302

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