Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Modified Research Career Development Award (K04)
Project #
5K04HL000945-05
Application #
3073588
Study Section
Biophysics and Biophysical Chemistry B Study Section (BBCB)
Project Start
1981-07-01
Project End
1986-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
Schools of Medicine
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Notter, R H; Shapiro, D L; Ohning, B et al. (1987) Biophysical activity of synthetic phospholipids combined with purified lung surfactant 6000 dalton apoprotein. Chem Phys Lipids 44:1-17
Matalon, S; Holm, B A; Notter, R H (1987) Mitigation of pulmonary hyperoxic injury by administration of exogenous surfactant. J Appl Physiol 62:756-61
Holm, B A; Notter, R H; Leary, J F et al. (1987) Alveolar epithelial changes in rabbits after a 21-day exposure to 60% O2. J Appl Physiol 62:2230-6
Ross, G F; Notter, R H; Meuth, J et al. (1986) Phospholipid binding and biophysical activity of pulmonary surfactant-associated protein (SAP)-35 and its non-collagenous COOH-terminal domains. J Biol Chem 261:14283-91
Leary, J F; Finkelstein, J N; Notter, R H et al. (1986) A quantitative study of the development of type II pneumocytes in fetal lung. Cytometry 7:431-8
Whitsett, J A; Ohning, B L; Ross, G et al. (1986) Hydrophobic surfactant-associated protein in whole lung surfactant and its importance for biophysical activity in lung surfactant extracts used for replacement therapy. Pediatr Res 20:460-7
Holm, B A; Notter, R H; Finkelstein, J N (1985) Surface property changes from interactions of albumin with natural lung surfactant and extracted lung lipids. Chem Phys Lipids 38:287-98
Notter, R H; Egan, E A; Kwong, M S et al. (1985) Lung surfactant replacement in premature lambs with extracted lipids from bovine lung lavage: effects of dose, dispersion technique, and gestational age. Pediatr Res 19:569-77
Holm, B A; Notter, R H; Siegle, J et al. (1985) Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia. J Appl Physiol 59:1402-9