This Geriatric Mental Health Academic Award application proposes a series of clinical investigations of geriatric neuropsychiatric disorders, including Alzheimer-type dementia, late-onset depression, and drug-induced attentional disruptions. The Principal Investigator will also be working with two groups of junior faculty to develop their research skills in geriatric and neurophsychiatric clinical research. He will catalyze the development of novel educational programs at the University of Rochester Medical Center as a means of disseminating new findings from geriatric mental health research to students, residents, faculty, and part-time physicians. The Principal Investigator will undertake a series of educational experiences to improve his skills for future investigations of elderly individuals. These will include learning more about: i) behavioral and psychophysical methods for assessing attentional dysfunction; ii) epidemiology, and iii) research design and data analysis. The Department of Psychiatry, University of Rochester School of Medicine and Dentistry, is committed to developing a vigorous program of geriatric mental health research. It has a unique setting and many of the resources necessary for accomplishing an exciting amalgamation of interests and skills in neuropsychiatry and clinical geriatric psychiatry. The Geriatric Mental Health Academic Award will facilitate the development of this creative endeavor.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07MH000473-03
Application #
3077704
Study Section
(LCRB)
Project Start
1983-07-01
Project End
1986-09-30
Budget Start
1985-07-01
Budget End
1986-09-30
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
Schools of Medicine
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Magee, J C; Avery, R B; Christie, B R et al. (1996) Dihydropyridine-sensitive, voltage-gated Ca2+ channels contribute to the resting intracellular Ca2+ concentration of hippocampal CA1 pyramidal neurons. J Neurophysiol 76:3460-70
Schiffer, R B; Caine, E D (1991) The interaction between depressive affective disorder and neuropsychological test performance in multiple sclerosis patients. J Neuropsychiatry Clin Neurosci 3:28-32
Bamford, K A; Caine, E D; Kido, D K et al. (1989) Clinical-pathologic correlation in Huntington's disease: a neuropsychological and computed tomography study. Neurology 39:796-801
Shoulson, I; Odoroff, C; Oakes, D et al. (1989) A controlled clinical trial of baclofen as protective therapy in early Huntington's disease. Ann Neurol 25:252-9
Chiverton, P; Caine, E D (1989) Education to assist spouses in coping with Alzheimer's disease. A controlled trial. J Am Geriatr Soc 37:593-8
Kido, D K; Caine, E D; LeMay, M et al. (1989) Temporal lobe atrophy in patients with Alzheimer disease: a CT study. AJNR Am J Neuroradiol 10:551-5
Cushman, L A; Como, P G; Booth, H et al. (1988) Cued recall and release from proactive interference in Alzheimer's disease. J Clin Exp Neuropsychol 10:685-92
Caine, E D; McBride, M C; Chiverton, P et al. (1988) Tourette's syndrome in Monroe County school children. Neurology 38:472-5
Caine, E D; Bamford, K A; Schiffer, R B et al. (1986) A controlled neuropsychological comparison of Huntington's disease and multiple sclerosis. Arch Neurol 43:249-54
Caine, E D (1985) Differentiating depression from Alzheimer's disease. Bull Clin Neurosci 50:5-6