Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
3K08HL000694-05S1
Application #
3081578
Study Section
Research Manpower Review Committee (MR)
Project Start
1980-07-01
Project End
1985-11-30
Budget Start
1984-07-01
Budget End
1985-11-30
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Meloni, F J; Gustafson, E J; Schmaier, A H (1992) High molecular weight kininogen binds to platelets by its heavy and light chains and when bound has altered susceptibility to kallikrein cleavage. Blood 79:1233-44
Pixley, R A; Schmaier, A; Colman, R W (1987) Effect of negatively charged activating compounds on inactivation of factor XIIa by Cl inhibitor. Arch Biochem Biophys 256:490-8
Schmaier, A H; Schutsky, D; Farber, A et al. (1987) Determination of the bifunctional properties of high molecular weight kininogen by studies with monoclonal antibodies directed to each of its chains. J Biol Chem 262:1405-11
Gluszko, P; Rucinski, B; Musial, J et al. (1987) Fibrinogen receptors in platelet adhesion to surfaces of extracorporeal circuit. Am J Physiol 252:H615-21
Gustafson, E J; Schutsky, D; Knight, L C et al. (1986) High molecular weight kininogen binds to unstimulated platelets. J Clin Invest 78:310-8
Schmaier, A H; Smith, P M; Purdon, A D et al. (1986) High molecular weight kininogen: localization in the unstimulated and activated platelet and activation by a platelet calpain(s). Blood 67:119-30
Schmaier, A H; Bradford, H; Silver, L D et al. (1986) High molecular weight kininogen is an inhibitor of platelet calpain. J Clin Invest 77:1565-73
Schmaier, A H; Smith, P M; Colman, R W (1985) Platelet C1- inhibitor. A secreted alpha-granule protein. J Clin Invest 75:242-50