The overall goal of this Geriatric Academic Program (GAP) award proposal is to develop future academic leaders in geriatric medicine and geriatric psychiatry. Junior faculty physicians who have excelled in a geriatric fellowship program will be selected to undergo an intensive three year training experience in geriatric research, teaching, and clinical practice. At the end of each awardee's three year period, she or he will have the skills to be an independent investigator and teacher in geriatrics and gerontology in an academic medical center. At the end of the five year funding period, 6 awardees (3 psychiatry and 3 internal medicine geriatricians) will have been trained. A large group of University of Washington faculty with interest, experience, and support in geriatric and gerontologic research have agreed to serve as potential sponsors and mentors. Each mentor, together with an individual steering committee, will develop and closely monitor the junior faculty awardee's plans and progress. Overall direction for the program will be provided by the program director, who heads the University of Washington Division of Gerontology and Geriatric Medicine, and the program co-director, who heads the University of Washington Division of Geriatric Psychiatry. Sample research training plans and projects for the two candidates already chosen for year 01 are included. Dorcas Dobie, M.D., is a senior fellow in geriatric psychiatry. She proposes to study vasopressin gene expression in aging. David Gruenewald, M.D., is a senior fellow in geriatric medicine. He proposes to study aging and brain regulation of male reproduction.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12AG000503-03
Application #
3088050
Study Section
Aging Review Committee (AGE)
Project Start
1991-01-01
Project End
1995-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Levy, Wayne C; Maichel, Barbara A; Steele, Natalie P et al. (2004) Biomechanical efficiency is decreased in heart failure during low-level steady state and maximal ramp exercise. Eur J Heart Fail 6:917-26
Mitchell, Steven H; Steele, Natalie P; Leclerc, Kenneth M et al. (2003) Oxygen cost of exercise is increased in heart failure after accounting for recovery costs. Chest 124:572-9
Stratton, John R; Levy, Wayne C; Caldwell, James H et al. (2003) Effects of aging on cardiovascular responses to parasympathetic withdrawal. J Am Coll Cardiol 41:2077-83
Levy, W C; Cerqueira, M D; Weaver, W D et al. (2001) Early patency of the infarct-related artery after myocardial infarction preserves diastolic filling. Am J Cardiol 87:955-8; A3
Tsuang, D; Almqvist, E W; Lipe, H et al. (2000) Familial aggregation of psychotic symptoms in Huntington's disease. Am J Psychiatry 157:1955-9
Leclerc, K M; Steele, N P; Levy, W C (2000) Norepinephrine alters exercise oxygen consumption in heart failure patients. Med Sci Sports Exerc 32:2029-34
Gruenewald, D A; Naai, M A; Marck, B T et al. (2000) Age-related decrease in hypothalamic gonadotropin-releasing hormone (GnRH) gene expression, but not pituitary responsiveness to GnRH, in the male Brown Norway rat. J Androl 21:72-84
Unutzer, J; Katon, W; Sullivan, M et al. (1999) Treating depressed older adults in primary care: narrowing the gap between efficacy and effectiveness. Milbank Q 77:225-56, 174
Tsuang, D; DiGiacomo, L; Lipe, H et al. (1998) Familial aggregation of schizophrenia-like symptoms in Huntington's disease. Am J Med Genet 81:323-7
Levy, W C; Cerqueira, M D; Harp, G D et al. (1998) Effect of endurance exercise training on heart rate variability at rest in healthy young and older men. Am J Cardiol 82:1236-41

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