This is a competitive renewal application for continued support of a postdoctoral research career development program for obstetrician-gynecologists in fundamental research in reproductive medicine and biology. It is sponsored jointly by the NIH/NICHD, six professional organizations, three pharmaceutical corporations, and three research foundations. The objective of this program is to educate obstetrician-gynecologists in contemporary basic science research to prepare them for research careers in academic medicine. The goal is to help ensure that academic obstetrics and gynecology fulfills its mission to increase research and discovery in the reproductive sciences. Outstanding PhD and MD scientists with broad research experience serve as faculty. A unique feature of this program is that outstanding individuals, upon completion of residency, and in many cases two or three years of clinical subspecialty fellowship, spend two to three years in fundamental research laboratories under the supervision and mentorship of experienced, well-screened, and accomplished scientists (Phase I). Following this experience, scholars spend an additional three-year period establishing their research programs in a Department of Obstetrics and Gynecology (Phase II). During Phase I, scholars are dedicated to full-time research. Following this basic research, the scholar spends three years as a junior faculty member in a Department of Obstetrics and Gynecology with at least 75% time free to develop an independent research career. Phase II is funded from a number of possible sources, including NIH and private grants, and from contributions to the RSDP program from the profession, from philanthropic foundations, industry, and personal sources. Upon completion of this program, the candidate is expected to continue to pursue a career as a productive investigator. This program serves as a model to educate increased numbers of reproductive scientists to develop into leaders in academic Departments of Obstetrics and Gynecology. The RSDP's plan for career development serves as a model for postgraduate medical education, and assures that some of the most promising young physician-investigators in the country will remain in academic investigative obstetrics and gynecology. A great majority of the scholars who have finished Phase II of the Program have dedicated themselves to research in the reproductive sciences and have developed major independent funding support. To date their productivity has been outstanding, and is a credit to the Program.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD000849-22
Application #
7672309
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Parrott, Estella C
Project Start
1988-09-01
Project End
2013-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
22
Fiscal Year
2009
Total Cost
$1,551,244
Indirect Cost
Name
University of California San Francisco
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Elias, Kevin M; Tsantoulis, Petros; Tille, Jean-Christophe et al. (2018) Primordial germ cells as a potential shared cell of origin for mucinous cystic neoplasms of the pancreas and mucinous ovarian tumors. J Pathol 246:459-469
Salati, Jennifer A; Roberts, Victoria H J; Schabel, Matthias C et al. (2018) Maternal high-fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity. Int J Obes (Lond) :
Scroggins, Sabrina M; Santillan, Donna A; Lund, Jenna M et al. (2018) Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia. Clin Sci (Lond) 132:419-436
Hirsch, Alec J; Roberts, Victoria H J; Grigsby, Peta L et al. (2018) Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology. Nat Commun 9:263
Vazquez, Jessica; Chavarria, Melina; Li, Yan et al. (2018) Computational flow cytometry analysis reveals a unique immune signature of the human maternal-fetal interface. Am J Reprod Immunol 79:
Qin, Chunrong; Xia, Xi; Fan, Yanhong et al. (2018) A novel, noncoding-RNA-mediated, post-transcriptional mechanism of AMH regulation by the H19/let-7 axis. Biol Reprod :
Han, Michelle N; O'Donnell, Betsy E; Maykin, Melanie M et al. (2018) The impact of cerclage in twin pregnancies on preterm birth rate before 32 weeks. J Matern Fetal Neonatal Med :1-9
Bandoli, Gretchen; Jelliffe-Pawlowski, Laura L; Feuer, Sky K et al. (2018) Second trimester serum cortisol and preterm birth: an analysis by timing and subtype. J Perinatol 38:973-981
Mills, Kathryn A; Roach, S Tanner; Quinn, Jeanne M et al. (2018) SQ1274, a novel microtubule inhibitor, inhibits ovarian and uterine cancer cell growth. Gynecol Oncol 151:337-344
Mhatre, Mohak; Adeli, Sharareh; Norwitz, Errol et al. (2018) The Effect of Maternal Obesity on Placental Cell-Free DNA Release in a Mouse Model. Reprod Sci :1933719118811647

Showing the most recent 10 out of 294 publications