UTMB-Galveston and the Ob/Gyn Department respectively submit this competing application to continue our RHR Career Development Center. We have trained 5 Scholars: 3 women and 2 men--1 underrepresented minority investigator and 1 disabled investigator; all scholars were drawn from diverse clinical specialties; 3 initially had virtually no research experience; and 1 earned her PhD as a Scholar. We commit to achieving all goals as set forth by the RFA: The Department has broad-based, basic research in important women's reproductive health problems and has greatly increased both translational research and clinical research (ranks 8th in number of NIH grants awarded to Ob/Gyn departments, FY 2002). The Mentors for the WRHR Scholars, both from within the Ob/Gyn Department and from other departments, have experience training physicians who want to become independent investigators. This effect is further enhanced by Ob/Gyn Mentors having a dual appointment in the following: Anatomy & Neurosciences, Microbiology, Pediatrics, Physiology, Surgery, Psychiatry, the Sealy Center for Molecular Science, and the Marine Biology Institute. We have a group of excellent WRHR Scholar candidates, and our fellowship programs, all of which require 18 months of basic research and a Masters of Science degree, will continue to produce well qualified candidates. The research laboratories of the Ob/Gyn Mentors (equal to approximately 32,000 sq ft) are modern and well equipped as are the laboratories of the Mentors from other departments. The environment both in the Department and UTMB is supportive of developing young physicians who want research careers. Research has been of the highest priority since Dr. Anderson became the Chair 14 years ago, and some of the key personnel in this grant developed their research careers in our own Department. UTMB has demonstrated its support of this grant both by monies; increased clinical, administrative, and research space within the Department; and adherence to the 75% protected research time. Both the Department and UTMB have demonstrated their commitment to recruitment and promotion of women physicians and underrepresented minority physicians. (UTMB Medical School ranked first in United States in awarding medical degrees to Hispanics and seventh to African Americans.) We have the necessary infrastructure to successfully train young physicians to become independent investigators in areas that address important women's reproductive health concerns.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD001269-09
Application #
7233949
Study Section
Special Emphasis Panel (ZHD1-DSR-A (20))
Program Officer
Parrott, Estella C
Project Start
1998-09-30
Project End
2009-04-30
Budget Start
2007-05-01
Budget End
2008-04-30
Support Year
9
Fiscal Year
2007
Total Cost
$398,863
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
Borahay, Mostafa A; Fang, Xiao; Baillargeon, Jacques G et al. (2016) Statin use and uterine fibroid risk in hyperlipidemia patients: a nested case-control study. Am J Obstet Gynecol 215:750.e1-750.e8
Patel, Pooja R; Lee, Jinhyung; Hirth, Jacqueline et al. (2016) Changes in the Use of Contraception at First Intercourse: A Comparison of the National Survey of Family Growth 1995 and 2006-2010 Databases. J Womens Health (Larchmt) 25:777-83
Theiler, Regan N; Snyder, Russell R; Theiler, Shaleen K (2015) Dystroglycan in human fetal membranes decreases in later gestation and with spontaneous membrane rupture. Gynecol Obstet Invest 79:244-9
Borahay, Mostafa A; Vincent, Kathleen; Motamedi, Massoud et al. (2015) Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study. Am J Obstet Gynecol 213:196.e1-8
Patel, Pooja R; Laz, Tabassum H; Berenson, Abbey B (2015) Patient characteristics associated with pregnancy ambivalence. J Womens Health (Larchmt) 24:37-41
Patel, Pooja R; Lee, Jinhyung; Rodriguez, Ana M et al. (2014) Disparities in use of laparoscopic hysterectomies: a nationwide analysis. J Minim Invasive Gynecol 21:223-7
Patel, Pooja Rani (2014) Putting medical risks into perspective. Clin Pract (Lond) 11:35-37
Lee, Jinhyung; Jennings, Kristofer; Borahay, Mostafa A et al. (2014) Trends in the national distribution of laparoscopic hysterectomies from 2003 to 2010. J Minim Invasive Gynecol 21:656-61
Berenson, Abbey B; Patel, Pooja R; Barrett, Alan D (2014) Is administration of the HPV vaccine during pregnancy feasible in the future? Expert Rev Vaccines 13:213-9
Borahay, Mostafa A; Kilic, Gokhan S; Yallampalli, Chandrasekha et al. (2014) Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells. J Biol Chem 289:35075-86

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