description): Designed in response to this RFA, the BIRCWH Program at University of North Carolina (UNC) will consist of a Principal Investigator (PI), Program Director (PD), an Advisory Committee, and a group of carefully selected and dedicated mentors. The PI on this application, Dr. Eugene Orringer, is the Executive Associate Dean for Faculty Affairs, and has considerable authority for faculty appointments. The PD is Bruce Lessey, PhD, MD, a faculty member in the Department of Obstetrics and Gynecology and a senior investigator with expertise in the training of both basic scientists and clinical researchers. The Advisory Committee is composed of senior leaders and scholars from a wide variety of Departments, Centers, and Schools within the University, each of whom was selected because of a demonstrated interest in and expertise relevant to women's health research. Finally, the mentors chosen for this BIRCWH Program are broadly representative of the diverse research environment that exists at UNC, and will provide outstanding training opportunities for all of the selected IRWH Scholars. The research plan is built around three central themes: Biomarkers to Therapeutics; Prevention and Intervention; and Health Issues of the Mature Woman. These themes were selected because each is relevant to women's health, well-suited to interdisciplinary collaboration, and emphasizes an area of particular strength at UNC.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD001441-02
Application #
6387393
Study Section
Special Emphasis Panel (ZHD1-MCHG-B (08))
Program Officer
Davis Nagel, Joan
Project Start
2000-09-22
Project End
2005-07-31
Budget Start
2001-08-01
Budget End
2002-07-31
Support Year
2
Fiscal Year
2001
Total Cost
$500,000
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Harris, Sarah; Vora, Neeta L (2018) Maternal Genetic Disorders in Pregnancy. Obstet Gynecol Clin North Am 45:249-265
Carlson, Laura M; Hardisty, Emily; Coombs, Catherine C et al. (2018) Maternal Malignancy Evaluation After Discordant Cell-Free DNA Results. Obstet Gynecol 131:464-468
Best, Sunayna; Wou, Karen; Vora, Neeta et al. (2018) Promises, pitfalls and practicalities of prenatal whole exome sequencing. Prenat Diagn 38:10-19
Vora, Neeta L; Grace, Matthew R; Smeester, Lisa et al. (2018) Targeted Multiplex Gene Expression Profiling to Measure High-Fat Diet and Metformin Effects on Fetal Gene Expression in a Mouse Model. Reprod Sci :1933719118786453
Jelin, Angie C; Vora, Neeta (2018) Whole Exome Sequencing: Applications in Prenatal Genetics. Obstet Gynecol Clin North Am 45:69-81
Harris, Sarah; Reed, Dallas; Vora, Neeta L (2018) Screening for fetal chromosomal and subchromosomal disorders. Semin Fetal Neonatal Med 23:85-93
Shen, Mark D; Nordahl, Christine W; Li, Deana D et al. (2018) Extra-axial cerebrospinal fluid in high-risk and normal-risk children with autism aged 2-4 years: a case-control study. Lancet Psychiatry 5:895-904
Croffut, Samantha E; Hamela, Gloria; Mofolo, Innocent et al. (2018) HIV-positive Malawian women with young children prefer overweight body sizes and link underweight body size with inability to exclusively breastfeed. Matern Child Nutr 14:
Carlson, Laura M; Harris, Sarah; Hardisty, Emily E et al. (2018) Use of a novel computerized decision aid for aneuploidy screening: a randomized controlled trial. Genet Med :
Vora, Neeta L; Wapner, Ronald J (2018) Introducing new and emerging genetic tests into prenatal care. Semin Perinatol 42:283-286

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