K12 Abstract The Children's Hospital of Philadelphia (CHOP) Child Health Research Career Development Award (CHRCDA) K12 Training Program is intended to foster the maturation of pediatric junior faculty into independent physician-scientists who are skilled in cutting-edge methods of laboratory research and who pursue long-term academic careers investigating important issues related to childhood health and disease. The CHOP CHRCDA Program is based on a pool of outstanding candidates, a large group of experienced mentors who perform state-of-the-art laboratory research, a robust research environment, and a comprehensive array of career development opportunities. The Principal Investigator/Program Director and the Training Director will receive assistance from two Diversity Recruitment Officers, an Internal Advisory Committee, and an External Advisory Committee in selecting scholars, reviewing the progress of scholars, and ensuring the optimal operation of the program. Three scholars will be supported each year and will be drawn from junior faculty in the Department of Pediatrics, with particular emphasis on recruitment of women, underrepresented minorities, individuals with disabilities, and other disadvantaged individuals. The Program Faculty mentors have been drawn from the Department of Pediatrics, the Department of Pathology, and the Department of Surgery at CHOP and from a range of clinical and basic science departments at the University of Pennsylvania (Penn). The Program Faculty have been selected based on a strong track record in research that is germane to pediatrics, extramural funding, and mentoring. The CHRCDA Scholars will conduct research as outlined in their formal research applications and will have access to all shared facilities and to the full spectrum of core facilities at CHOP and Penn. The CHRCDA Scholars will also benefit from the opportunity to pursue a wide range of career development activities, including coursework, workshops, and other special educational and training experiences. The CHOP CHRCDA Program will build on the impressive success of the 27 CHOP CHRCDA Scholars over the past 15 years and the 63 CHOP CHRCDA Scholars over the past 25 years.

Public Health Relevance

The overall goal of this CHRCDA program is to identify, train, and mentor promising pediatric faculty to become successful independent physician-scientists addressing questions of fundamental importance to health and disease in children. The CHOP CHRCDA Program will increase the number and effectiveness of subspecialty pediatricians with rigorous background and skills in basic and translational research. In turn, these individuals will speed the transfer of knowledge gained through studies in basic and translational science to clinical applications that will benefit the health of children.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD043245-18
Application #
9825550
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Bremer, Andrew
Project Start
2003-04-11
Project End
2022-11-30
Budget Start
2019-12-01
Budget End
2020-11-30
Support Year
18
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19146
Swarr, Daniel T; Peranteau, William H; Pogoriler, Jennifer et al. (2018) Novel Molecular and Phenotypic Insights into Congenital Lung Malformations. Am J Respir Crit Care Med 197:1328-1339
Pinz, Hailey; Pyle, Louise C; Li, Dong et al. (2018) De novo variants in Myelin regulatory factor (MYRF) as candidates of a new syndrome of cardiac and urogenital anomalies. Am J Med Genet A 176:969-972
Henrickson, Sarah E; Walter, Jolan E; Quinn, Colin et al. (2018) Adult-Onset Myopathy in a Patient with Hypomorphic RAG2 Mutations and Combined Immune Deficiency. J Clin Immunol 38:642-645
Zacharias, William J; Frank, David B; Zepp, Jarod A et al. (2018) Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. Nature 555:251-255
Henrickson, Sarah E; Manne, Sasikanth; Dolfi, Douglas V et al. (2018) Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection. Cell Rep 22:411-426
Ruffner, Melanie A; Henrickson, Sarah E; Chilutti, Marianne et al. (2018) Improving allergy office scheduling increases patient follow up and reduces asthma readmission after pediatric asthma hospitalization. Ann Allergy Asthma Immunol 121:561-567
Sengupta, S; Haczku, A (2017) Targeting I?BNS in allergic asthma: where it resides, matters. Allergy 72:1003-1005
Wenger, Tara L; Dahl, John; Bhoj, Elizabeth J et al. (2017) Tracheal cartilaginous sleeves in children with syndromic craniosynostosis. Genet Med 19:62-68
Zepp, Jarod A; Zacharias, William J; Frank, David B et al. (2017) Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung. Cell 170:1134-1148.e10
Tuttle, Katherine L; Schneider, Thomas R; Henrickson, Sarah E et al. (2016) Aspirin-exacerbated respiratory disease: not always ""adult-onset"". J Allergy Clin Immunol Pract 4:756-8

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