Abstract

Using the panhandle polymerase chain reaction (PCR), I am amplifying and characterizing the viral-human genomic junctions in two tissue culture cell lines and in cervical and oral carcinoma clinical samples. Although most gave PCR products, the sequence showed viral sequence only. However, one clinical sample revealed one human/viral junction. A search on GenBank failed to reveal close homology with other published sequences.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Unknown (K16)
Project #
2K16DE000175-11
Application #
5210046
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Perinpanayagam, H; Schneider, G; Holtman, K et al. (2004) Altered Cbfa1 expression and biomineralization in an osteosarcoma cell line. J Orthop Res 22:404-10
Armstrong, Steven R; Vargas, M A; Chung, I et al. (2004) Resin-dentin interfacial ultrastructure and microtensile dentin bond strength after five-year water storage. Oper Dent 29:705-12
Timmons, Sherry R; Nwankwo, Joseph O; Domann, Frederick E (2002) Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes. Oral Oncol 38:281-90
Armstrong, S R; Keller, J C; Boyer, D B (2001) The influence of water storage and C-factor on the dentin-resin composite microtensile bond strength and debond pathway utilizing a filled and unfilled adhesive resin. Dent Mater 17:268-76
Armstrong, S R; Keller, J C; Boyer, D B (2001) Mode of failure in the dentin-adhesive resin-resin composite bonded joint as determined by strength-based (muTBS) and fracture-based (CNSB) mechanical testing. Dent Mater 17:201-10
Armstrong, S R; Boyer, D B; Keller, J C et al. (1998) Effect of hybrid layer on fracture toughness of adhesively bonded dentin-resin composite joint. Dent Mater 14:91-8
Armstrong, S R; Boyer, D B; Keller, J C (1998) Microtensile bond strength testing and failure analysis of two dentin adhesives. Dent Mater 14:44-50
Kurago, Z B; Lutz, C T; Smith, K D et al. (1998) NK cell natural cytotoxicity and IFN-gamma production are not always coordinately regulated: engagement of DX9 KIR+ NK cells by HLA-B7 variants and target cells. J Immunol 160:1573-80
Baumgardner, K R; Walton, R E; Osborne, J W et al. (1996) Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention. J Dent Res 75:1753-60
Kurago, Z B; Smith, K D; Lutz, C T (1995) NK cell recognition of MHC class I. NK cells are sensitive to peptide-binding groove and surface alpha-helical mutations that affect T cells. J Immunol 154:2631-41

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