This proposal requests funding for five years to establish an institutional Dentist Scientist Award (DSA) program at the University of California at San Francisco (UCSF) School of Dentistry. The program will enroll two DSA trainees annually who will pursue a program that integrates basic science knowledge and a research experience in a subdiscipline (biomaterials, cell interactions and tissue remodelling, craniofacial growth and development, neurobiology, viral and bacterial pathogenesis, host response) embodied within the Ph.D. programs in Oral Biology or Bioengineering. Clinical specialty certification will be obtained in one of six clinical areas: oral and maxillofacial surgery, oral medicine, orthodontics, pediatric dentistry, periodontology or prosthodontics. The basic program will require 7 years and proposes augmentation of the 5-years of DSA funding with 2-years support from other sources. The program offers a variety of choices in research areas, individually tailored training programs, dedicated mentoring, and the opportunity for participation in research at the leading edges of biomedical science, with clinical education and training from well established and widely recognized specialty areas of excellence. The program builds on the research and clinical environment at UCSF and specific experiences with advanced training of dentists in their Ph.D. programs, as well as ongoing experiences with individual DSA trainees. Approximately 70 mentors and co-mentors will participate in the program offering scientific and clinical programs and resources. The establishment of the DSA is envisioned as a means of bringing these """"""""diverse elements together to provide a cohesive effort that links and integrates leading edge scientific development with dental care"""""""". The overall goal of the proposal is to provide trainees with a much broader scientific and clinical perspective than would be possible by participating in the isolated components of the program. This approach is thought to provide future leadership in the form of dental clinician-scientists in dental medicine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Unknown (K16)
Project #
5K16DE000386-07
Application #
6516336
Study Section
Special Emphasis Panel (ZDE1-GH (26))
Program Officer
Gordon, Sharon M
Project Start
1996-07-01
Project End
2004-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
7
Fiscal Year
2002
Total Cost
$245,911
Indirect Cost
Name
University of California San Francisco
Department
Dentistry
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Gallagher, R R; Balooch, M; Balooch, G et al. (2010) Coupled Nanomechanical and Raman Microspectroscopic Investigation of Human Third Molar DEJ. J Dent Biomech 2010:
Sroussi, Herve Y; Köhler, Gerwald A; Agabian, Nina et al. (2009) Substitution of methionine 63 or 83 in S100A9 and cysteine 42 in S100A8 abrogate the antifungal activities of S100A8/A9: potential role for oxidative regulation. FEMS Immunol Med Microbiol 55:55-61
Hyde, S; Satariano, W A; Weintraub, J A (2006) Welfare dental intervention improves employment and quality of life. J Dent Res 85:79-84
Sroussi, H Y; Berline, J; Dazin, P et al. (2006) S100A8 triggers oxidation-sensitive repulsion of neutrophils. J Dent Res 85:829-33
Hyde, Susan; Weintraub, Jane A; Satariano, William A (2005) An evaluation of the San Francisco Department of Human Services Welfare Dental Program. J Public Health Dent 65:104-9
Gallagher, R R; Demos, S G; Balooch, M et al. (2003) Optical spectroscopy and imaging of the dentin-enamel junction in human third molars. J Biomed Mater Res A 64:372-7
Schmidt, Brian L; Tambeli, Claudia H; Levine, Jon D et al. (2003) Adaptations in nucleus accumbens circuitry during opioid withdrawal associated with persistence of noxious stimulus-induced antinociception in the rat. J Pain 4:141-7
Yeomans, David C; Onyuksel, Hayat; Dagar, Sumeet et al. (2003) Conformation-dependent effects of VIP on nociception in rats. Peptides 24:617-22
Chainani-Wu, Nita (2003) Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med 9:161-8
Rubinstein, Israel; Pedersen, Gerald W (2002) Bacillus species are present in chewing tobacco sold in the United States and evoke plasma exudation from the oral mucosa. Clin Diagn Lab Immunol 9:1057-60

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