The purpose of this study is to evaluate differences in parasympathetic effects on adrenergic receptor function between hostile/Type A (coronary- prone) and nonhostile/Type B (noncoronary-prone) individuals. Our previous work has shown larger beta receptor-mediated electrophysiologic responses to isoproterenol infusion among hostile Type A's. We hypothesize that this effect is due to deficient vagal protection of the ventricular myocardium against sympathetic effects among hostile Type A's.

Project Start
Project End
Budget Start
Budget End
Support Year
34
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
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