Triple therapy treatment with antiviral agents seems to suppress the level of HIV in the blood below limits of detection. The combination of indinavir (a protease inhibitor) +zidovudine (AZT) + lamivudine (3TC) has been shown to suppress the level of RNA and reduce the rate of clinical disease progression. The addition of delavirdine results in 2-5 times higher indinavir levels.

Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
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