This is a double-blind, placebo controlled, randomized parallel group study conducted in two stages comparing 4 levels of ribavirin (400, 600, 800, and 1000-1200 mg/day) + Intron A 3 MU TIW and Intron A 3 MU TIW + placebo in patients with chronic hepatitis C who have not previously been treated with interferon. All subjects will receive 24 weeks of therapy, and will have an additional 24 weeks of follow up. Stage 1 will identify which dose of ribavirin to be utilized in stage 2.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR000037-39S1
Application #
6113117
Study Section
Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
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