This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study seeks to clarify the role of depression on cardiovascular risk by studying the effects of depression on the cardiovascular system using a co-twin study design. The group will consist of Vietnam Era veteran twin pairs without clinical evidence of coronary artery disease, who are discordant for major depression.
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