This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This K23 award is to conduct a randomized trial to determine whether a more 'physiologic' insulin regimen (short acting insulin before meals and intermediate-acting insulin at bedtime) improves hemoglobin A1c more than conventional insulin therapy (usually 70-30 insulin twice a day) in a predominantly low-income, African American population with type 2 dia
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