RS-61443 (Mycophenolate mofetil), the morpholino-ethyl ester of mycophenolic acid (MPA), is being evaluated as an immunosuppressant agent for use following solid organ transplantation. MPA is a potent and specific inhibitor of de novo purine synthesis and blocks the proliferation of both T and B lymphocytes. This will be the first multi-center-controlled study evaluating the safety and pharmacokinetics of intravenous mycophenolate mofetil.

Project Start
Project End
Budget Start
Budget End
Support Year
36
Fiscal Year
1996
Total Cost
Indirect Cost
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