This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Changes in dermal capillary blood flow and blood oxygen deliver to deep tissue in response to a brief period of hypoxia will be studied in normal controls and subjects with sickle cell anemia. These responses will be standardized so they can later be used to study pharmacological interventions that may improve blood flow and oxygen delivery. Blood oxygen level delivery will be measured by magnetic resonance imaging and dermal capillary blood flow will be measured using laser-Doppler flow.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000043-47
Application #
7603962
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-12-01
Project End
2007-11-30
Budget Start
2006-12-01
Budget End
2007-11-30
Support Year
47
Fiscal Year
2007
Total Cost
$36,827
Indirect Cost
Name
University of Southern California
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
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