This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. One intriguing line of research that may have broad public health application in this regarding is the role of breakfast habits on rates of obesity. For a number of behavioral and physiological reasons, the breakfast meal may be of unique importance with respect to appetite control, dietary quality, and obesity risk. In children and adolescents, breakfast skipping prevalence is reported to range from 12 to 34% and to increase with age. Numerous observational studies have explored the association between breakfast frequency and risk of obesity, with most noting an inverse association. owever, only a few small short-term randomized trials have been conducted on this topic. Therfore, to fully address whether the frequency of eating breakfast, and the type of breakfast eaten, may play an important role in energy balance, dietary quality, and obesity risk, we propse to conduct a 2-center randomized crossover trial of breakfast intervention in a group of at-risk-for-overweight (85th-94th age/gender appropriate BMI percentiles) and overweight (95th and ablove BMI percentiles) 14-16 year old Latino boys who habitually consume breakfast less than four times per week. THe intervention will include supplying breakfast foods, along with instruction, over 3 week treatment periods so that we can evaluate effects of both breakfast frequency (7days/wk v. usual intake) and quality (whole foods balanced v. highly processed meals) on various outcomes. We hypothesize that increased breakfast frequency and quality will result in improved metabolic, behavioral, and psycological outcomes.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000043-49
Application #
7982130
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-12-01
Project End
2009-11-30
Budget Start
2008-12-01
Budget End
2009-11-30
Support Year
49
Fiscal Year
2009
Total Cost
$31,306
Indirect Cost
Name
University of Southern California
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Kelsey, Megan M; Braffett, Barbara H; Geffner, Mitchell E et al. (2018) Menstrual Dysfunction in Girls From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study. J Clin Endocrinol Metab 103:2309-2318
Davis, J N; Asigbee, F M; Markowitz, A K et al. (2018) Consumption of artificial sweetened beverages associated with adiposity and increasing HbA1c in Hispanic youth. Clin Obes 8:236-243
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Kriska, Andrea; El Ghormli, Laure; Copeland, Kenneth C et al. (2018) Impact of lifestyle behavior change on glycemic control in youth with type 2 diabetes. Pediatr Diabetes 19:36-44
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Detterich, Jon A (2018) Simple chronic transfusion therapy, a crucial therapeutic option for sickle cell disease, improves but does not normalize blood rheology: What should be our goals for transfusion therapy? Clin Hemorheol Microcirc 68:173-186
Gidding, Samuel S; Bacha, Fida; Bjornstad, Petter et al. (2018) Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study. J Pediatr 192:86-92.e5
Cooper, Aaron R; Lill, Georgia R; Shaw, Kit et al. (2017) Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients. Blood 129:2624-2635
Arslanian, Silva; El Ghormli, Laure; Bacha, Fida et al. (2017) Adiponectin, Insulin Sensitivity, ?-Cell Function, and Racial/Ethnic Disparity in Treatment Failure Rates in TODAY. Diabetes Care 40:85-93

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