This unit serves a facility for carrying out clinical research projects on hospitalized patients and normal subjects. Examples of projects on this unit include studies of: Hypercoagulability and Thrombosis; Growth Hormone in Pituitary Disorders; Genetic Disorders of Central Nervous System; Alcoholic Hepatitis; Bleeding Esophageal Varices; Physiology and Kinetics of Leukocytes; Intestinal Peptide Hydrolases; Chronic Active Hepatitis; Epidermolysis Bullosa; Home Intravenous Hyperalimentation; BCNU, Medrol, Procarbazine, and Radiotherapy in Treatment of Brain Tumors; Gross Peptic Esophagitis; Muco-Cutaneous Candidiasis; Bartters Syndrome; Dietary Protein, Calcium and Phosphorus; Propylthiouracil and Methimazole in Early Treatment of Hyperthroidism; Caloric Deprivation and Weight Reduction in Diabetic Control; Overnutrition and Thyroid Hormone Regulation; Adenocarcinoma Unknown Primary Evaluation; Pathogenesis of Bullosa Pemphigoid; Ectopic Hormones in Non-Endocrine Malignancy; Thyrotropin Physiology; Effects of Smoking on Codeine Disposition; Hyperbaric Oxygenation Treatments for Extracranial-Intracranial Arterial Anastomosis; Immunotherapy for Patients with Anaplastic Gliomas; Adenine Therapy for Fanconi Anemia; Clinical-Pathologic Correlation of Ocular Sarcoidosis; Acyclovir Administered to Immunocompromised Children with Varicella Zoster, Herpes Simplex and Cytomegalovirus Infections; Somatomedin-C in Acromegaly; Lymphokin Treatment of Laryngeal Papillomatosis.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
General Clinical Research Centers Program (M01)
Project #
Application #
Study Section
Special Emphasis Panel (SRC)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of North Carolina Chapel Hill
Schools of Medicine
Chapel Hill
United States
Zip Code
Little, Jayne; Parker, Ben; Lunt, Mark et al. (2018) Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort. Rheumatology (Oxford) 57:677-687
Abdullah, Lubna H; Coakley, Raymond; Webster, Megan J et al. (2018) Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia. Am J Respir Crit Care Med 197:481-491
Martin, Maureen P; Naranbhai, Vivek; Shea, Patrick R et al. (2018) Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest 128:1903-1912
Haas, David W; Bradford, Yuki; Verma, Anurag et al. (2018) Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events. Pharmacogenet Genomics 28:179-187
Venuto, Charles S; Lim, Jihoon; Messing, Susan et al. (2018) Inflammation investigated as a source of pharmacokinetic variability of atazanavir in AIDS Clinical Trials Group protocol A5224s. Antivir Ther 23:345-351
Malinen, Melina M; Kauttonen, Antti; Beaudoin, James J et al. (2018) Novel In Vitro Method Reveals Drugs that Inhibit Solute Transporter Alpha/Beta (OST?/?). Mol Pharm :
Li, Binglan; Verma, Shefali S; Veturi, Yogasudha C et al. (2018) Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pac Symp Biocomput 23:448-459
Hanly, John G; Li, Qiuju; Su, Li et al. (2018) Cerebrovascular Events in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study. Arthritis Care Res (Hoboken) 70:1478-1487
Barber, Megan R W; Hanly, John G; Su, Li et al. (2018) Economic Evaluation of Lupus Nephritis in the Systemic Lupus International Collaborating Clinics Inception Cohort Using a Multistate Model Approach. Arthritis Care Res (Hoboken) 70:1294-1302
Rini, Christine; Vu, Maihan B; Lerner, Hannah et al. (2018) A qualitative study of patient and provider perspectives on using web-based pain coping skills training to treat persistent cancer pain. Palliat Support Care 16:155-169

Showing the most recent 10 out of 782 publications