The HIV protease enzyme is essential for HIV infection. L-735,524 is a specific inhibitor of this enzyme and inhibits HIV in vitro. This study in HIV infected subjects is designed to assess the safety and effect on virus levels of this medication given with zidovudine (ZDV, a standard therapy) or given alone compared with ZDV given alone.

Project Start
1997-01-06
Project End
1997-11-30
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
37
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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