The purpose of this research study is to compare the ability of different types of Neisseria gonorrhoeae (the organism responsible for gonorrhea), to cause a clinical infection, (signs or symptoms of urethritis such as discomfort in urination, urethral discharge, etc). We predict that the changes we have identified or engineered in some gonococci will render them less capable of causing infection. This study will greatly enhance our understanding of the biology of gonorrhea, and potentially help us to develop a vaccine against this organism, by pointing towards parts of the bacteria that are critical for infection.

Project Start
1999-12-01
Project End
2000-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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