This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The purpose of this K01 career development award is to provide training and supervised research in a new area of study. We will examine how cocaine use in pregnancy alters maternal physiological systems involved in maternal attachment formation in humans. Focus will be on dysregulation of maternal oxytocin activity, maternal behavior during video-taped infant interaction, and fMRI measures of maternal brain circuitry in response to infant cues. Subjects will be 48 mother-infant dyads(with prenatal cocaine use vs. drug naieve). Mothers will undergo an experimental lab with their infants, 24-hour monitoring in the home environment, and a short fMRI protocol.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000046-48
Application #
7716873
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-04-02
Project End
2008-05-31
Budget Start
2008-04-02
Budget End
2008-05-31
Support Year
48
Fiscal Year
2008
Total Cost
$3,673
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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