This is a multicenter chemoprevention seven year clinical trial using finasteride to reduce the incidence of prostate cancer in healthy men. Finasteride is a 5-alpha-reductase inhibitor which may play a pivotal role in the initialization and progression of prostate cancer. After an initial run-in period, volunteers without evidence of prostate enlargement and with a normal PSA will be randomized to receive either daily finasteride or matched placebo for 7 years or until development of prostate-related symptoms. Progress report and summary of findings: This prostate cancer prevention trial is a double blind placebo, controlled trial, which remains ongoing. As such, there are no results on outcome to report at this point in time. No adverse experiences have been encountered at NYH- CUMC.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
38
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
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