Patients with advanced measurable metastatic malignant melanoma are treated with oral melatonin. The dose is escalated by 25 percent in groups of 3 patients starting at 75 mg/m2. Patients are then followed for response and toxicity with particular emphasis on measurement of gonadotropin and thyroid hormones.

Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
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