This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This study investigates the efficacy of an early environmental with children at risk for asthma. In addition this study also investigates the natural history of asthma and the psychosocial and environmental issues surrounding childhood asthma in a low-income population. This proposal follows the progress of the subjects previously enrolled in the Childhood Asthma Prevention Study (CAPS). The subjects were enrolled because they had 3 or more physician-documented episodes of wheezing prior to the age of 2 and were from low-income families. Both of these factors put them at risk for childhood asthma. In the previous phase of the CAPS study, the families were randomized into two different intervention groups. Those families in the treatment condition had a nurse home-visitor work with them for a year on an asthma management protocol. The families in the information control group received written information about asthma management only. At four years of age, the children were assessed for asthma status. This proposal follows these children until the age of 7 years when asthma status will again be assessed to test the efficacy of the intervention. The families will be contacted to begin this follow-up when the children are 6 years old. The follow-up will then continue for a year until the children are 7 when they come into National Jewish for a medical evaluation.
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