This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This study is being done to learn more about why atopic dermatitis patients get more viral skin infections such as Herpes simplex. When atopic dermatitis patients get disseminated skin outbreaks with herpes simplex virus, that condition is called eczema herpeticum (EH). Investigators are looking for the genes that increase the risk of having this condition. Changes in a gene can mean that some people may be more likely to have eczema herpeticum than others. The genes of patients who have eczema herpeticum will be compared to the genes of people who do not have this condition. Investigators have chosen to focus upon EH because it is felt to represent a reasonable, 'real-life' surrogate for eczema vaccinatum (EV). EV is a severe and life threatening reaction to the smallpox vaccine.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000051-47
Application #
7719398
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-04-01
Project End
2008-05-31
Budget Start
2008-04-01
Budget End
2008-05-31
Support Year
47
Fiscal Year
2008
Total Cost
$2,096
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
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