Although the ketogenic diet has been used for more than 70 years, it is rarely used outside of centers with extensive experience in its use & extensive dietary experience & support. Much still needs to be learned about its efficacy for controlling different seizure types, its effects on EEG's & pharmacological treatment, its long term effects & its mechanism of action. Traditionally the ketogenic diet has been used in young children, between the ages of 2 & 6 years, with myoclonic, atonic, & tonic clonic seizures. Although some studies have indicated that the diet is not as effective in partial or absence seizures, the data to support these studies has not been substantiated. The purpose of this study is to assess if the classic ketogenic diet is efficacious in reducing seizure frequency, decreasing medication toxicity & improving quality of life in children with intractable seizures.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000052-40
Application #
6457696
Study Section
Special Emphasis Panel (ZRR1)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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