The purpose of this investigation is to compare the effects of FemHRT, Evista, and PremPro, on vasomotor symptom relief, vaginal bleeding/spotting, lipid profiles, bone mineral density, and biochemical markers of bone metabolism. We hypothesize that FemHRT will :[1] be as effective as Prempro in reducing vasomotor symptoms;[2] provide better control of breakthrough bleeding/spotting; and [3] will have similar effects on lipid profiles, bone mineral density, and bone metabolism in early postmenopausal women. We further hypothesize that FemHRT will be more effective than Evista in; [1] reducing vasomotor symptoms;[2] controlling breakthrough bleeding; and [3] improving bone density, bone metabolism, and lipid profiles in early postmenopausal women.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000056-40
Application #
6459743
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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