Perimenopause is the period of time before actual menopause occurs and is often characterized by irregular menstrual cycles due to fluctuating estrogen levels. Hot flushes (warmth that begins on the face and radiates to the neck and chest, often accompanied by red flush) are experienced by approximately 80% of women once circulatory estrogen levels are decreased. Certain plant chemicals called phytoestrogens can modify or mimic the action of reproductive hormones in humans and whose biological actions suggest that they may provide natural protection for women from symptoms such as hot flushes. This study will test two doses of isoflavones, a phytoestrogen in a soy dietary supplement for the treatment of hot flushes in perimenopausal and menopausal women.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000056-40
Application #
6459745
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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