The General Clinical Research Center is the major setting for clinical investigations by the faculty of Medical College of Wisconsin. Our GCRC continues its efforts to elucidate mechanisms of disease and new therapeutic modalities. The current and proposed major areas include: 1) mechanisms of insulin resistance and abnormal insulin dynamics in abdominal obesity and its progression towards NIDDM; 2) metabolic heterogeneity of lipoprotein transport and modes of action of fish oil supplementation; 3) dietary and endocrine deficiencies in the elderly; 4) hemodynamic physiology and regulation of vascular resistance in hypertension; 5) hemodynamics of pulmonary hypertension; 6) biological and biochemical modulations for cancer; 7) control of gastrointestinal motility and epithelial transport in health and disease; 8) biochemical mechanisms of nephrolithiasis; 9) immunopathology and therapy of endemic pemphigus foliaceous; 10) cellular, molecular and clinical features of common hematologic disorders; 11) NIV/AIDS behavior research; 12) pathogenesis and treatment of benign prostatic hyperplasia; 13) retinal pathology and treatment.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000058-31
Application #
3089499
Study Section
General Clinical Research Centers Committee (CLR)
Project Start
1991-12-01
Project End
1996-11-30
Budget Start
1992-02-11
Budget End
1992-11-30
Support Year
31
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Eastman, Meridith L; Verhulst, Brad; Rappaport, Lance M et al. (2018) Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization. Behav Genet 48:421-431
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