Abstract

The purpose of this project is to validate that genetic mutation at codon 215 of reverse transcriptase appears in the blood of HIV patients before viral load increases and T4 cells decrease, and to determine whether patients on zidovudine who develop this mutation change their viral titer and number of T4 cells when given a combination of other anti-HIV drugs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000059-38
Application #
6114715
Study Section
Project Start
Project End
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
38
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Type
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Rao, Satish S C; Valestin, Jessica A; Xiang, Xuelian et al. (2018) Home-based versus office-based biofeedback therapy for constipation with dyssynergic defecation: a randomised controlled trial. Lancet Gastroenterol Hepatol 3:768-777
Curtis, Alexandra M; VanBuren, John; Cavanaugh, Joseph E et al. (2018) Longitudinal associations between dental caries increment and risk factors in late childhood and adolescence. J Public Health Dent 78:321-328
Lorenz, Douglas J; Levy, Steven; Datta, Somnath (2018) Inferring marginal association with paired and unpaired clustered data. Stat Methods Med Res 27:1806-1817
Oweis, Reem Reda; Levy, Steven M; Eichenberger-Gilmore, Julie M et al. (2018) Fluoride intake and cortical and trabecular bone characteristics in adolescents at age 17: A prospective cohort study. Community Dent Oral Epidemiol 46:527-534
Curtis, A M; Cavanaugh, J E; Levy, S M et al. (2018) Examining caries aetiology in adolescence with structural equation modelling. Community Dent Oral Epidemiol 46:258-264
Askie, Lisa M; Darlow, Brian A; Finer, Neil et al. (2018) Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA 319:2190-2201
Choo-Wosoba, Hyoyoung; Gaskins, Jeremy; Levy, Steven et al. (2018) A Bayesian approach for analyzing zero-inflated clustered count data with dispersion. Stat Med 37:801-812
Levy, Steven M; Eichenberger-Gilmore, Julie M; Warren, John J et al. (2018) Associations of fluoride intake with children's cortical bone mineral and strength measures at age 11. J Public Health Dent 78:352-359
Denson, Lee A; McDonald, Scott A; Das, Abhik et al. (2017) Early Elevation in Interleukin-6 is Associated with Reduced Growth in Extremely Low Birth Weight Infants. Am J Perinatol 34:240-247
Bell, Edward F; Johnson, Karen J; Dove, Edwin L (2017) Effect of Body Position on Energy Expenditure of Preterm Infants as Determined by Simultaneous Direct and Indirect Calorimetry. Am J Perinatol 34:493-498

Showing the most recent 10 out of 381 publications