This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. From the perspective of fundamental science, the elucidation of brain/mind relationships has long been a key intellectual enterprise and is arguably the last frontier in the life sciences. The results obtained through this research are also valuable in terms of applied science, and will yield knowledge relevant to the understanding, diagnosis, management and treatment of many neurological and psychiatric conditions, principally, cerebrovascular disease, head injury, cerebral tumors, epilepsy, Alzheimer's disease and sociopathy. Moreover, several neuroimaging and cognitive tools developed for experimental purposes have improved diagnostic strategies and procedures, and have allowed the development of new remediation programs. Findings from these studies are critical to computational modeling of cognitive and neural processes with biological realism.
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