This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Nearly 50% of extremely low birth weight (ELBW) infants have abnormal neurodevelopmental and/or sensory findings at 18 to 22 months adjusted age. The early identification of adverse developmental sequelae is important not only to ascertain the medium and long-term effects of medical therapies in the nursery, but also to afford the best opportunity for addressing potential developmental delays and disabilities with early interventions. Formal developmental testing is expensive, and may be limited in its availability outside of metropolitan areas, making serial formal evaluations impractical. The accuracy of professionally administered developmental screenings and assessments is enhanced when parent input regarding a child's current behavior and development is elicited. The Ages and Stages Questionnaire (ASQ), a parent-administered developmental screening tool, may be a cost-effective alternative to expensive, serial professionally administered developmental evaluations. The specific goals of this project are to examine: 1) if developmental trends, as determined by the parent-administered ASQ at 4 age points (4, 8, 12, and 18 months corrected age), predict the results obtained on formal, professionally administered developmental testing at 18-22 months corrected age; and 2) the relationship between the results of the 18-22 month corrected age ASQ, administered by parents, with the results of this professionally administered evaluation.
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