The effect of growth hormone on insulin, insulin-like growth factor and bone mineral metabolism will be studied in children with growth failure from chronic renal failure. Bone density will be monitored by dual energy x-ray absorptiometry and insulin metabolism will be studied by hyperglycemic clamp methodology. Primary study end points will be growth velocity standard deviation score, insulin secretion and bone density.

Project Start
Project End
Budget Start
Budget End
Support Year
34
Fiscal Year
1996
Total Cost
Indirect Cost
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