This is a randomized, double-blind controlled trial of pulse loaded IV clomipramine (CMI), (day 1 150 mg; day 2 200 mg, days 3-6 zero) pulse loaded oral CMI and placebo (oral-plus-i.v.) in patients with treatment- unresponsive obsessive compulsive (OCD). Primary hypothesis: IV pulse loaded CMI will produce by day 6 a clinically meaningful improvement in OCR patients and this improvement will significantly exceed that produced by oral pulse-loaded CMI and placebo.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
36
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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