This multicenter, randomized, double-blind, placebo-controlled, dose-ranging study will assess the efficacy, safety, and pharmacokientic characteristics of daily doses of the vasopressin V2 antagonist OPC-41061 in patients with hyponatremia secondary to liver disease. The study attempts to determine whether OPC-41061 may play a role in controlling ascites and/or peripheral edema in patients with liver disease.

Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
36
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
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