This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Background: The increasing numbers of overweight children and adolescents poses a major threat to America's health. Although the Centers for Disease Control, U.S. Department of Education, and Texas Department of Health provide schools with guidelines to improve their physical education (PE), the best way to evaluate these guidelines is not established. Therefore, their actual benefit is unknown.Hypothesis: Our hypothesis is that newer high school exercise programs can help reverse the heart abnormalities that occur in overweight youngsters.
Specific Aims and Procedures: After a physical examination and answering a questionnaire, the students will undergo some testing before and after participate in one of two different physical education courses. One course will be no different from those taught presently. The other will be a newly designed program that is in greater accordance with state and national guidelines. The tests that will be performed include an electrocardiogram (ECG), a form of heart rhythm analysis called heart rate variability, and a heart sonogram (echocardiogram). Some blood will be drawn for analysis of blood sugar, insulin, a hormone called leptin, and fatty acid.Experimental Design: We will determine whether the new PE course is an improvement over the present-day course by seeing if beneficial changes occur in the tests that were obtained before the course began. Significance: Overweight adolescents are at increased risk of developing diabetes, heart disease, and high blood pressure. These problems will significantly decrease their quality of life and life expectancy, and will greatly increase the costs of health care.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000073-45
Application #
7719181
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-04-01
Project End
2009-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
45
Fiscal Year
2008
Total Cost
$662
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
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