This is a pilot study to examine differences in clinical outcomes when three strtegies are utilized for switching subjects with schizophrenia or schizoaffective disorder from treatment with currently available antipsychotic agents to treatment with ziprasidone. The discovery of novel antipsychotic medications that have significant clinical advantages over typical antipsychotics has prompted many clinicians to treat their patients with these newer drugs. Treatment failures have occurred with these agents despite their demonstrated efficacy. Part of the reason my lie in the abrupt withdrawal of one medication and the addition of a new one with significantly different pharmacological profile.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
36
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
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